Publications

Plasma rejuvenation factor GDF11 associates with amyloid-related cognitive decline in older adults across the Alzheimer’s Disease spectrum.

Shannon Y. Lee, Emily W. Paolillo, Rowan Saloner, Anna M VandeBunte, Gil D. Rabinovici, Renaud La Joie, Joel H. Kramer, Saul Villeda, Kaitlin B. Casaletto

2023
Phospholipase D3 drives microglial response to amyloid pathology in Alzheimer’s disease.

Matthew J Rosene, Emma Danhash, Shih-Feng You, Abhirami Kannan Iyer, Simon Hsu, Mariana Acquarone de Sa Lopes, Logan Brase, Anthony Verbeck, Rita Martinez, Clare E Wallace, Zeran Li, Ping Yan, Nina Drager, Sydney M Sattler, Thomas E Mahan, Shannon L Macauley, David M. Holtzman, Bruno A. Benitez, Martin Kampmann, Carlos Cruchaga, Oscar Harari, John R Cirrito, Jin-Moo Lee, Alison Goate, Celeste M. Karch

2023
Multiomics of iPSC-derived ApoE3- and ApoE4 astrocytes and microglia uncovers cell type specific dysregulation of immunometabolism.

Rik van der Kant, Niek Blomberg, Lena Erlebach, Femke M Feringa, Jorin Heijneman, Sascha Koppes, Iris Daphne Kruijff, Amanda McQuade, Ricardo Miramontes, Damien Olivier-Jimenez, Aiko Robert, Leslie M. Thompson, Alessandro Ori, Deborah Kronenberg-Versteeg, Yassene Mohammed, Martin Kampmann, Martin Giera

2023
Alzheimer’s disease risk genes modulate interferon-responsive microglia.

Amanda McQuade, Vincent Cele Castillo, Nina Drager, Martin Kampmann

2023
Relationships between KLOTHO and APOE4-associated ß-amyloid and tau alterations across AD continuum.

Noah R. Cook, Ira Driscoll, Catherine L. Gallagher, Sterling C Johnson, Sanjay Asthana, Bruce P Hermann, Mark A. Sager, Kaj Blennow, Henrik Zetterberg, Cynthia M. Carlsson, Gwendlyn Kollmorgen, Margherita Carboni, Dan Wang, Dena B. Dubal, Ozioma Okonkwo

2023
Klotho protein concentrations as a function of sex, APOE, family history or Alzheimer’s disease biomarker status in an at-risk cohort.

Ira Driscoll, Tobey J Betthauser, Catherine L. Gallagher, Bruce P Hermann, Mark A. Sager, Cynthia M. Carlsson, Gwendlyn Kollmorgen, Margherita Carboni, Dan Wang, Kaj Blennow, Henrik Zetterberg, Sterling C Johnson, Sanjay Asthana, Dena B. Dubal, Ozioma Okonkwo

2023
Neurotrophin NT-4/5 Promotes Structural Changes in Neurons of the Developing Visual Cortex.

Antonini A, Harris SL, Stryker MP

2023
High-throughput PRIME-editing screens identify functional DNA variants in the human genome.

Ren X, Yang H, Nierenberg JL, Sun Y, Chen J, Beaman C, Pham T, Nobuhara M, Takagi MA, Narayan V, Li Y, Ziv E, Shen Y

2023
Sensitization of Human and Rat Nociceptors by Low Dose Morphine is TLR4-dependent.

Khomula EV, Levine JD

2023
Mapping general anesthesia states based on electro-encephalogram transition phases.

Loison V, Voskobiynyk Y, Lindquist B, Necula D, Longrois D, Paz J, Holcman D

2023

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