bioRxiv : the preprint server for biology

Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold.

Deconvolution of polygenic risk score in single cells unravels cellular and molecular heterogeneity of complex human diseases.

Stress hyperglycemia exacerbates inflammatory brain injury after stroke.

Regulatory T cell-derived enkephalin imparts pregnancy-induced analgesia.

Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration.

Closed-loop modulation of remote hippocampal representations with neurofeedback.

Dual α-globin and truncated EPO receptor knockin restores hemoglobin production in α-thalassemia-derived red blood cells.

Unifying community-wide whole-brain imaging datasets enables robust automated neuron identification and reveals determinants of neuron positioning in C. elegans.

Sex Differences In The Interaction Between Alcohol And mTORC1.

Massively parallel reporter assays and mouse transgenic assays provide complementary information about neuronal enhancer activity.

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