Cancer cell

Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha.

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells.

Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha.

DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma.

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma.

Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene.

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