Docking 14 Million Virtual Isoquinuclidines against the µ and ? Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects.

Vigneron SF, Ohno S, Braz J, Kim JY, Kweon OS, Webb C, Billesbølle CB, Srinivasan K, Bhardwaj K, Irwin JJ, Manglik A, Basbaum AI, Ellman JA, Shoichet BK. Docking 14 Million Virtual Isoquinuclidines against the µ and ? Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects. ACS Cent Sci. 2025 May 28; 11(5):770-790.

2025
https://researcherprofiles.org/profile/618805241
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Vigneron SF, Ohno S, Braz J, Kim JY, Kweon OS, Webb C, Billesbølle CB, Srinivasan K, Bhardwaj K, Irwin JJ, Manglik A, Basbaum AI, Ellman JA, Shoichet BK