Human molecular genetics

Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping.

Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations.

Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations.

Genomic context drives SCA7 CAG repeat instability, while expressed SCA7 cDNAs are intergenerationally and somatically stable in transgenic mice.

Genomic context drives SCA7 CAG repeat instability, while expressed SCA7 cDNAs are intergenerationally and somatically stable in transgenic mice.

Multiple susceptibility loci for multiple sclerosis.

Multiple susceptibility loci for multiple sclerosis.

A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.

A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.

Multilocus linkage identifies two new loci for a mendelian form of stroke, cerebral cavernous malformation, at 7p15-13 and 3q25.2-27.

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