The Journal of clinical investigation

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.

Serine 421 regulates mutant huntingtin toxicity and clearance in mice.

Serine 421 regulates mutant huntingtin toxicity and clearance in mice.

Cross-species translation of the Morris maze for Alzheimer's disease.

Cross-species translation of the Morris maze for Alzheimer's disease.

Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch.

Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch.

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.

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