Journal of virology

Mapping the prion protein using recombinant antibodies.

Mapping the prion protein using recombinant antibodies.

Propagation of prion strains through specific conformers of the prion protein.

Propagation of prion strains through specific conformers of the prion protein.

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.

Failure to transmit disease from gray tremor mutant mice.

Failure to transmit disease from gray tremor mutant mice.

Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity.

Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity.

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