The mitochondrial DNA of Drosophila melanogaster exists in two distinct and stable superhelical forms.

Rubenstein JL, Brutlag D, Clayton DA. The mitochondrial DNA of Drosophila melanogaster exists in two distinct and stable superhelical forms. Cell. 1977 Oct; 12(2):471-82.

1977
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Rubenstein JL, Brutlag D, Clayton DA