Molecular cell

High-throughput PRIME-editing screens identify functional DNA variants in the human genome.

Activation and closed-state inactivation mechanisms of the human voltage-gated KV4 channel complexes.

NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.

STL-seq reveals pause-release and termination kinetics for promoter-proximal paused RNA polymerase II transcripts.

Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent.

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids.

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.

Design principles of regulatory networks: searching for the molecular algorithms of the cell.

Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1a.

Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1a.

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