Predicting expression-altering promoter mutations with deep learning.

Science (New York, N.Y.)

Jaganathan K, Ersaro N, Novakovsky G, Wang Y, James T, Schwartzentruber J, Fiziev P, Kassam I, Cao F, Hawe J, Cavanagh H, Lim A, Png G, McRae J, Banerjee A, Kumar A, Ulirsch J, Zhang Y, Aguet F, Wainschtein P, Sundaram L, Salcedo A, Kyriazopoulou Panagiotopoulou S, Aghamirzaie D, Padhi E, Weng Z, Dong S, Smedley D, Caulfield M, O'Donnell-Luria A, Rehm HL, Sanders SJ, Kundaje A, Montgomery SB, Ross MT, Farh KK. Predicting expression-altering promoter mutations with deep learning. Science. 2025 May 29; eads7373.

2025
https://researcherprofiles.org/profile/633398695
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Jaganathan K, Ersaro N, Novakovsky G, Wang Y, James T, Schwartzentruber J, Fiziev P, Kassam I, Cao F, Hawe J, Cavanagh H, Lim A, Png G, McRae J, Banerjee A, Kumar A, Ulirsch J, Zhang Y, Aguet F, Wainschtein P, Sundaram L, Salcedo A, Kyriazopoulou Panagiotopoulou S, Aghamirzaie D, Padhi E, Weng Z, Dong S, Smedley D, Caulfield M, O'Donnell-Luria A, Rehm HL, Sanders SJ, Kundaje A, Montgomery SB, Ross MT, Farh KK