Publications

Reversal of C9orf72 mutation-induced transcriptional dysregulation and pathology in cultured human neurons by allele-specific excision.

Aradhana Sachdev, Kamaljot Gil, Maria Sckaff, Alisha M Birk, Olubankole Aladesuyi Arogundade, Katherine A Brown, Runvir S Chouhan, Patrick Issagholian Lewin, Esha Patel, Kathleen Keough, Bruce Conklin, Alec ST Smith, Claire Clelland

2024
KLOTHO KL-VS genotype modifies the relationship between cardiorespiratory fitness and CSF biomarkers of neurodegeneration, synaptic dysfunction, and inflammation.

Mackenzie Jarchow, Ira Driscoll, Brianne M. Breidenbach, Noah R. Cook, Catherine L. Gallagher, Sterling C. Johnson, Sanjay Asthana, Bruce P Hermann, Mark A. Sager, Kaj Blennow, Henrik Zetterberg, Cynthia M. Carlsson, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Dane B. Cook, Dena B. Dubal, Ozioma C Okonkwo

2024
Uncovering mechanisms of hyperexcitability in tauopathies with functional genomics.

Steven C Boggess, Vaidehi Gandhi, Ming-Chi Tsai, Yu-Ying Chou, Jesse E. Hanson, Martin Kampmann

2024
Exploring selective neuronal vulnerability in Alzheimer’s disease – key pathways are downregulated in vulnerable subpopulations of RORB and CDH9 excitatory neurons of the entorhinal cortex at Braak 0.

Alexander V. Soloviev, Felipe Luiz Pereira, Renata Elaine Paraizo Leite, Claudia Kimie Suemoto, Kun Leng, Martin Kampmann, Lea T. Grinberg

2024
Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis.

Magliozzi R, Hametner S, Mastantuono M, Mensi A, Karimian M, Griffiths L, Watkins LM, Poli A, Berti GM, Barusolo E, Bellini B, Rossi S, Gveric D, Stratton JA, Akassoglou K, Magon S, Nicholas R, Reynolds R, Howell OW, Monaco S

2024
Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.

Lopez-Lee C, Kodama L, Fan L, Zhu D, Zhu J, Wong MY, Ye P, Norman K, Foxe NR, Ijaz L, Yu F, Chen H, Carling GK, Torres ER, Kim RD, Dubal DB, Liddelow SA, Sinha SC, Luo W, Gan L

2024
Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins.

Xu D, Besselink S, Ramadoss GN, Dierks PH, Lubin JP, Pattali RK, Brim JI, Christenson AE, Colias PJ, Ornelas IJ, Nguyen CD, Chasins SE, Conklin BR, Nuñez JK

2024
The commitment of the human cell atlas to humanity.

Amit I, Ardlie K, Arzuaga F, Awandare G, Bader G, Bernier A, Carninci P, Donnelly S, Eils R, Forrest ARR, Greely HT, Guigo R, Hacohen N, Haniffa M, Kirby ES, Knoppers BM, Kriegstein A, Lein ES, Linnarsson S, Majumder PP, Merad M, Meyer K, Mhlanga MM, Nolan G, Ntusi NAB, Pe'er D, Prabhakar S, Raven-Adams M, Regev A, Rozenblatt-Rosen O, Saha S, Saltzman A, Shalek AK, Shin JW, Stunnenberg H, Teichmann SA, Tickle T, Villani AC, Wells C, Wold B, Yang H, Zhuang X

2024

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