The Journal of biological chemistry

Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.

Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.

Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein.

Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein.

Ubiquitination in the first cytoplasmic loop of µ-opioid receptors reveals a hierarchical mechanism of lysosomal down-regulation.

Ubiquitination in the first cytoplasmic loop of µ-opioid receptors reveals a hierarchical mechanism of lysosomal down-regulation.

CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.

CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.

A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets.

A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets.

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