The Journal of biological chemistry

Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment.

Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment.

Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes.

Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes.

Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease.

Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease.

The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.

Engineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by Hrs.

Engineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by Hrs.

Alternative splicing determines the post-endocytic sorting fate of G-protein-coupled receptors.

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