Proceedings of the National Academy of Sciences of the United States of America

Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes.

A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex.

Reversal of C9orf72 mutation-induced transcriptional dysregulation and pathology in cultured human neurons by allele-specific excision.

Diverse roles of pontine NPS-expressing neurons in sleep regulation.

Phase separation of YAP-MAML2 differentially regulates the transcriptome.

The clustered gamma protocadherin PcdhγC4 isoform regulates cortical interneuron programmed cell death in the mouse cortex.

Population encoding of stimulus features along the visual hierarchy.

Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production.

Adaptor protein-3 produces synaptic vesicles that release phasic dopamine.

Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.

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