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Signal Transduction and Second Messenger Signaling in Pain Sensory Neurons; CNS Pain Control Mechanisms; Neural-Endocrine Control of Inflammation

Our laboratory employs a multidisciplinary approach of molecular, biochemical, in vitro and in vivo electrophysiological and behavioral techniques to evaluate mechanisms underlying pain and analgesia.

Understanding social attachment: Molecular and genetic approaches to study the neural basis of social attachment throughout development and in disease

Structural and Mechanistic Studies of Ion Channels and Ion Channel Regulation

Neurobiology of Diseases Affecting Cognitive Function

Areas of investigation
We study processes that result in memory loss and other major neurological deficits, with an emphasis on Alzheimer's disease and related neurodegenerative disorders. Our long-term goal is to advance the understanding of the healthy and the diseased central nervous system to a point where rational strategies can be developed for the prevention and cure of these conditions. 

The cellular and circuit mechanisms of movement disorders